The Best Nootropics to Improve Your Mood

 Still suffering a case of the Monday’s on Saturday?

Feeling down and finding it hard to focus? Nootropic supplements can help. 


Keep reading to learn more about some of the best OTC nootropics that can help improve your mood today.


Recipe For Natural Nootropic Blend


nootropic is a type of drug that can improve cognitive functions like memory, creativity, and motivation. The most common nootropic is caffeine, which is known to temporarily improve focus. 


Stronger nootropics, such as Adderall and Axura, are prescribed to treat the symptoms of cognitive illnesses like ADHD, narcolepsy, dementia and Alzheimer’s. 


Over-the-counter nootropics often referred to as “mood enhancers” or “smart drugs,” are used to treat a variety of common problems like stress, low mood, trouble sleeping, and brain fog. 


While research about nootropics is still ongoing, these drugs are said to work by improving the balance of excitatory and inhibitory neurotransmitters in the brain. This leads to lower stress levels, improved focus and mood, better sleep, and a sense of well-being. Unlike anti-depressants, nootropics provide wellness benefits with few side effects. 


Here are five of the most effective nootropics for improved mood:




One of the most powerful nootropics on the market, Noopept was originally designed for use by Russian astronauts.


Noopept is a peptide derivative shown to reduce stress and anxiety and improve mood, focus, memory, motivation, and energy. Noopept has also been shown to protect the brain from damage.


Noopept creates a sense of well-being by boosting the production of “feel-good” neurotransmitters dopamine and serotonin.




Aniracetam was developed in the 1970s to treat cognitive problems and boost brain performance; it does this by interacting with acetylcholine and glutamate receptors in the brain. 


Like Noopept, Aniracetam boosts mood by increasing the production of dopamine and serotonin in the brain.


Omega-3 Fatty Acids 


One of the most researched nootropics, Omega-3 fatty acids (AKA fish oil) are widely known to support heart and brain health. Omega-3’s are important because the body needs them but cannot synthesize them on its own. That means you must get them through diet or supplements.


As the name suggests, there are three types of Omega-3: ALA, EPA, and DHA. ALA must be converted into EPA or DHA by the body before it can be utilized. Unfortunately, our bodies aren’t very good at this, and most of the ALA we consume is used up as energy. 


EPA and DHA, which both come from fish, are known to improve mood and boost cognitive function. More specifically, EPA reduces anxiety, mood swings, and depression by controlling neuroinflammation and DHA boosts cognitive function by improving neural communication in the brain. 


When choosing a fish oil supplement for mood, make sure the product contains more EPA than DHA. 


By April Kuhlman




Like Omega-3’s, phosphatidylserine (PS) improves cognitive function by improving neural communication in the brain. PS improves mood and well-being by regulating serotonin, dopamine, and norepinephrine. 


PS can also improve mental stamina and improve sleep quality.




Originally prescribed in France for narcolepsy, Adrafinil is a powerful stimulant that increases alertness and fights fatigue. Benefits include heightened focus, lower anxiety, feelings of optimism, increased motivation, and improved memory/recall. 


Adrafinil acts like cocaine in that it produces good feelings by activating your dopamine receptors, but without the side effects. 


Tell us about your experience with nootropics in the comments section below!

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